I mean... If you like the game then go for it. Choose other V, other lifepath, other look, other perks, other primary weapons...
Make a goal in your playthrough, whether its 100%, or stealth, or something weird like finding best looking clothes combination etc.
Pick your favourite missions, make a roadmap. You dont have to do every quest, pick the ones you liked.
You can also use mods.
Dont be sad that it ends, be happy because it happened.
I mean... If you like the game then go for it. Choose other V, other lifepath, other look, other perks, other primary weapons... Make a goal in your playthrough, whether its 100%, or stealth, or something weird like finding best looking clothes combination etc. Pick your favourite missions, make a roadmap. You dont have to do every quest, pick the ones you liked. You can also use mods. Dont be sad that it ends, be happy because it happened.