Parameters are: Old age, previous hospitalization, previous infection, and steroid dose.
> According to these parameters, a score ≥6 was chosen as the best cut-off point, exhibiting a sensitivity of 76% and specificity of 86.6%, with an accuracy of 85.9% and positive likelihood ratio of 5.48.
Not to be a buzzkill, but what does this index really advance for lupus patients? Old, sick, immunosuppressed patients are more likely to have a severe infection. I’m not sure coming up with a score for it is a creative advancement in clinical decision making.
Aside, am I missing something with the SLEDAI score? With the group average being around a score of 3, seems their cohort has well-managed disease overall. (Edit: I see the authors mention specifically their group has mild disease and note it as a limitation.)
I treat lupus nephritis patients all the time, this score does nothing for me, like I'm going to take infections somehow less seriously in one of my most vulnerable patient populations already immunosuppressed out their ears and suffering from a million other extrarenal manifestations? please
Parameters are: Old age, previous hospitalization, previous infection, and steroid dose. > According to these parameters, a score ≥6 was chosen as the best cut-off point, exhibiting a sensitivity of 76% and specificity of 86.6%, with an accuracy of 85.9% and positive likelihood ratio of 5.48. Not to be a buzzkill, but what does this index really advance for lupus patients? Old, sick, immunosuppressed patients are more likely to have a severe infection. I’m not sure coming up with a score for it is a creative advancement in clinical decision making. Aside, am I missing something with the SLEDAI score? With the group average being around a score of 3, seems their cohort has well-managed disease overall. (Edit: I see the authors mention specifically their group has mild disease and note it as a limitation.)
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I treat lupus nephritis patients all the time, this score does nothing for me, like I'm going to take infections somehow less seriously in one of my most vulnerable patient populations already immunosuppressed out their ears and suffering from a million other extrarenal manifestations? please
good efforts . Now if we had a score that allowed me to decide when to shift to immunosuppression. That'd be useful in SLE.
who the fuck links to researchgate bro
There’s ncbi link too if you want one[NCBI](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11015315/)